A highly sensitive Atomic Force Microscope for linear measurements of molecular forces in liquids

Peter M. Hoffmann; Shivprasad Patil; George Matei; Hang Dong; Mustafa Karaköse; A. Oral

doi:10.1063/1.2083147

A highly sensitive Atomic Force Microscope for linear measurements of molecular forces in liquids

Peter M. Hoffmann, Shivprasad Patil, George Matei, Hang Dong, Mustafa Karaköse, A. Oral

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Abstract

We describe a highly improved atomic force microscope for quantitative nanomechanical measurements in liquids. The main feature of this microscope is a modified fiber interferometer mounted on a five axis inertial slider which provides a deflection sensitivity that is significantly better than conventional laser deflection based systems. The measured low noise floor of 572.0fm / Hz ⎯⎯⎯⎯⎯ √ 572.0 provides excellent cantilever amplitude resolution. This allows us to operate the instrument far below resonance at extremely small cantilever amplitudes of less than 1 1 Å. Thus linear measurements of nanomechanical properties of liquid systems can be performed. In particular, we present measurements of solvation forces in confined octamethylcyclotetrasiloxane and water with amplitudes smaller than the size of the respective molecules. In general, the development of the instrument is important in the context of quantitative nanomechanical measurements in liquid environments.

Original language	American English
Journal	Review of Scientific Instruments
DOIs	https://doi.org/10.1063/1.2083147
State	Published - 2005

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Physical Sciences and Mathematics

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title = "A highly sensitive Atomic Force Microscope for linear measurements of molecular forces in liquids",

abstract = " We describe a highly improved atomic force microscope for quantitative nanomechanical measurements in liquids. The main feature of this microscope is a modified fiber interferometer mounted on a five axis inertial slider which provides a deflection sensitivity that is significantly better than conventional laser deflection based systems. The measured low noise floor of 572.0fm / Hz ⎯⎯⎯⎯⎯ √ 572.0 provides excellent cantilever amplitude resolution. This allows us to operate the instrument far below resonance at extremely small cantilever amplitudes of less than 1 1 {\AA}. Thus linear measurements of nanomechanical properties of liquid systems can be performed. In particular, we present measurements of solvation forces in confined octamethylcyclotetrasiloxane and water with amplitudes smaller than the size of the respective molecules. In general, the development of the instrument is important in the context of quantitative nanomechanical measurements in liquid environments. ",

author = "Hoffmann, {Peter M.} and Shivprasad Patil and George Matei and Hang Dong and Mustafa Karak{\"o}se and A. Oral",

year = "2005",

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journal = "Review of Scientific Instruments",

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T1 - A highly sensitive Atomic Force Microscope for linear measurements of molecular forces in liquids

AU - Hoffmann, Peter M.

AU - Patil, Shivprasad

AU - Matei, George

AU - Dong, Hang

AU - Karaköse, Mustafa

AU - Oral, A.

PY - 2005

Y1 - 2005

N2 - We describe a highly improved atomic force microscope for quantitative nanomechanical measurements in liquids. The main feature of this microscope is a modified fiber interferometer mounted on a five axis inertial slider which provides a deflection sensitivity that is significantly better than conventional laser deflection based systems. The measured low noise floor of 572.0fm / Hz ⎯⎯⎯⎯⎯ √ 572.0 provides excellent cantilever amplitude resolution. This allows us to operate the instrument far below resonance at extremely small cantilever amplitudes of less than 1 1 Å. Thus linear measurements of nanomechanical properties of liquid systems can be performed. In particular, we present measurements of solvation forces in confined octamethylcyclotetrasiloxane and water with amplitudes smaller than the size of the respective molecules. In general, the development of the instrument is important in the context of quantitative nanomechanical measurements in liquid environments.

AB - We describe a highly improved atomic force microscope for quantitative nanomechanical measurements in liquids. The main feature of this microscope is a modified fiber interferometer mounted on a five axis inertial slider which provides a deflection sensitivity that is significantly better than conventional laser deflection based systems. The measured low noise floor of 572.0fm / Hz ⎯⎯⎯⎯⎯ √ 572.0 provides excellent cantilever amplitude resolution. This allows us to operate the instrument far below resonance at extremely small cantilever amplitudes of less than 1 1 Å. Thus linear measurements of nanomechanical properties of liquid systems can be performed. In particular, we present measurements of solvation forces in confined octamethylcyclotetrasiloxane and water with amplitudes smaller than the size of the respective molecules. In general, the development of the instrument is important in the context of quantitative nanomechanical measurements in liquid environments.

UR - https://aip.scitation.org/doi/10.1063/1.2083147

U2 - 10.1063/1.2083147

DO - 10.1063/1.2083147

M3 - Article

JO - Review of Scientific Instruments

JF - Review of Scientific Instruments

ER -

A highly sensitive Atomic Force Microscope for linear measurements of molecular forces in liquids

Abstract

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